The BIOMIS project envisages the establishment of the first Italian biobank of intestinal microbiota and human saliva with the aim of carrying out research activities aimed at identifying the relationships between microbiota and pathologies and testing innovative therapeutic approaches involving the transplantation of human microbiota in patients affected by specific diseases in order to modulate the patients' microbiota and restore the healthy one.
THE RESEARCH AND DEVELOPMENT PROJECT
The human microbiota is a very complex community of microorganisms, located at the mucosal level (in particular intestinal, oral and vaginal), containing a genome collectively referred to as "microbiome". Much research has highlighted the key role of the microbiota in human health.
Biomis foresees the realization of the first Italian biobank. It will allow to carry out research activities of excellence, which will be conducted with meta-homic approaches, in vitro and in vivo studies, and will be aimed at identifying new relationships between microbiota and pathologies. The ultimate goal will be also and above all therapeutic with the experimentation of innovative approaches in the treatment of pathological states.
Exprivia will develop the software platform to support the biobank with the ability to interface corporate and regional information systems (health registries, electronic health records, pathology networks, etc.) and to acquire large amounts of heterogeneous data (clinical, -omics, from scientific literature, etc.) to develop predictive models for diagnostic purposes and to support precision medicine.
PON “RESEARCH AND INNOVATION” 2014 - 2020 AND FSC
Project code ARS01_01220 - AXIS II - Action II Specific Objective 1.b
- District H-BIO Puglia, with the implementing subjects (members of the Consortium)
- Exprivia S.p.A.
- Gianni Benzi Foundation
- CNR IBIOM
- University of Bari Aldo Moro
- University of Salento
- IRCCS Istituto Tumori Giovanni Paolo II, Bari
- IRCCS De Bellis Castellana
- Catholic University of the Sacred Heart, Rome
- University of Perugia